Developing better animal models for universal influenza vaccines
Improving predictive capacity of models for universal influenza vaccine development
['FUNDING_R01'] · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · NIH-10672890
This study is working on making better flu vaccines by using special animal models to see how our bodies might react to the vaccine and the virus, helping to find ways to make the vaccines work even better for everyone.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (nih funded) |
| Locations | 1 site (MEMPHIS, UNITED STATES) |
| Trial ID | NIH-10672890 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the development of universal influenza vaccines by creating more accurate animal models that can predict how humans respond to immunization and infection. The team will optimize these models to better understand immune responses and improve vaccine efficacy testing. By studying how different animal models react to influenza, the researchers aim to identify key immune factors that can enhance vaccine effectiveness. This work is crucial for advancing public health and ensuring better protection against influenza.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals at high risk for influenza, such as infants, the elderly, and those with compromised immune systems.
Not a fit: Patients who are not at risk for influenza or who have already received effective vaccination may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective and universally protective influenza vaccines for patients.
How similar studies have performed: Previous research has shown promise in using animal models to study influenza, indicating that this approach has potential for success.
Where this research is happening
MEMPHIS, UNITED STATES
- ST. JUDE CHILDREN'S RESEARCH HOSPITAL — MEMPHIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WEBBY, RICHARD JOHN — ST. JUDE CHILDREN'S RESEARCH HOSPITAL
- Study coordinator: WEBBY, RICHARD JOHN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.