Developing better adjuvants for HIV vaccines

Rational Systemic Characterization and Selection of Adjuvants for HIV Vaccine Candidates (R-CASA)

['FUNDING_OTHER'] · SCRIPPS RESEARCH INSTITUTE, THE · NIH-11161215

This study is working on finding the best mixes of ingredients for an HIV vaccine to make it more effective, so that people can have better protection against the virus in the future.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorSCRIPPS RESEARCH INSTITUTE, THE (nih funded)
Locations1 site (LA JOLLA, UNITED STATES)
Trial IDNIH-11161215 on ClinicalTrials.gov

What this research studies

This research focuses on improving HIV vaccine development by identifying the best combinations of immunogens and adjuvants. The project will create standardized protocols and assays to systematically evaluate these combinations before they enter clinical trials. By screening various formulations, the research aims to enhance the effectiveness of future HIV vaccines, ultimately leading to better protection against the virus.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at risk of HIV infection who may benefit from improved vaccine options.

Not a fit: Patients who are already living with HIV and are seeking treatment rather than prevention may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective HIV vaccines that provide better immunity against the virus.

How similar studies have performed: Previous research has shown promise in developing effective adjuvants for vaccines, suggesting that this approach could yield significant advancements in HIV vaccine efficacy.

Where this research is happening

LA JOLLA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.