Developing antibody treatments for Duchenne's muscular dystrophy
DEVELOPMENT OF ENZYME-LINKED IMMUNOSORBENT ASSAYS (ELISAS) FOR NINDS NIH BLUEPRINT NEUROTHERAPEUTICS (BPN) BIOLOGICS PROJECT
This study is working on a new treatment for Duchenne's muscular dystrophy (DMD) using a special antibody, which could help improve the lives of patients by targeting the root causes of the condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Centers/pub Hlth Res & Evaluatn NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project ID | NIH-11250857 on NIH RePORTER |
What this research studies
This research focuses on creating and optimizing an antibody specifically designed to treat Duchenne's muscular dystrophy (DMD). The project involves evaluating the effectiveness of this antibody in pre-clinical studies and preparing it for clinical trials. Patients may benefit from the development of a new therapeutic option that targets the underlying causes of DMD, potentially improving their quality of life. The research will follow a structured approach, including in vivo efficacy evaluations and regulatory filings to ensure safety and effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Duchenne's muscular dystrophy.
Not a fit: Patients with other forms of muscular dystrophy or unrelated neuromuscular disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a new treatment option for patients with Duchenne's muscular dystrophy.
How similar studies have performed: Previous research has shown promise in developing antibody-based therapies for muscular dystrophies, indicating potential success for this approach.
Where this research is happening
Columbus, United States
- Battelle Centers/pub Hlth Res & Evaluatn — Columbus, United States (Active)
Researchers
- Principal investigator: Burnaugh, Amanda — Battelle Centers/pub Hlth Res & Evaluatn
- Study coordinator: Burnaugh, Amanda
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.