Developing antibody treatments for Duchenne's muscular dystrophy
Official title: DEVELOPMENT OF ENZYME-LINKED IMMUNOSORBENT ASSAYS (ELISAS) FOR NINDS NIH BLUEPRINT NEUROTHERAPEUTICS (BPN) BIOLOGICS PROJECT
Funded at Battelle Centers/pub Hlth Res & Evaluatn · NIH-11250857 · Data updated 2026-11-12
This study is working on a new treatment for Duchenne's muscular dystrophy (DMD) using a special antibody, which could help improve the lives of patients by targeting the root causes of the condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Centers/pub Hlth Res & Evaluatn NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project start | February 7, 2023 |
| Project end | February 6, 2028 |
| Funding year | 2025 |
| Award (this year) | $136,760 |
| NIH project number | 75N95022D00021-P00004-759502300001-1 |
| Project ID | NIH-11250857 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Duchenne's muscular dystrophy.
✕Less likely to help
Patients with other forms of muscular dystrophy or unrelated neuromuscular disorders may not benefit from this research.
What this research studies
This research focuses on creating and optimizing an antibody specifically designed to treat Duchenne's muscular dystrophy (DMD). The project involves evaluating the effectiveness of this antibody in pre-clinical studies and preparing it for clinical trials. Patients may benefit from the development of a new therapeutic option that targets the underlying causes of DMD, potentially improving their quality of life. The research will follow a structured approach, including in vivo efficacy evaluations and regulatory filings to ensure safety and effectiveness.
Why it matters
Potential benefit: If successful, this research could lead to a new treatment option for patients with Duchenne's muscular dystrophy.
How similar studies have gone: Previous research has shown promise in developing antibody-based therapies for muscular dystrophies, indicating potential success for this approach.
Where this research is happening
-
Battelle Centers/pub Hlth Res & Evaluatn
Columbus, United States Active
Researchers
- Principal investigator: Burnaugh, Amanda — Battelle Centers/pub Hlth Res & Evaluatn
- Study coordinator: Burnaugh, Amanda
Related research
Other NIH-funded projects on the same topics.
-
Testing the safety of vaccines and biologics for infectious diseases
This study is looking at new vaccines to help protect people from infectious diseases, including those that could come from bioterrorism, and aims to make these vaccines safer and more effective for everyone.
-
Monitoring heart and blood pressure changes in animals exposed to toxic chemicals
This study is looking at how tracking heart rate and blood pressure in animals can help us spot early signs of harm from toxic chemicals, which could lead to better ways to monitor and protect people from similar dangers.
-
Creating a system to test inhalation exposure to air pollutants in the lab
This study is working on a new lab system that safely tests how different air pollutants and toxic substances affect breathing, which could help us understand their impact on people and animals without using live tests.
-
Evaluating the effects of certain flame retardants on rats during development.
This study is looking at how certain chemicals, found in some products, might affect the health and development of baby rats when their mothers are pregnant or nursing, to help keep people safe from harmful substances.
-
Evaluating the health risks of naturally occurring asbestos and related mineral fibers.
This study is looking at how breathing in natural asbestos and similar fibers might harm health, especially the lungs, using tests on lab rats, to help keep people safe from these potential dangers.
-
Evaluating the toxic effects of mixed xylenes in animals
This study is looking into how breathing in mixed xylenes, which are chemicals we might encounter in our environment, could affect health, and it's designed to help us better understand any risks for people.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.