Developing antibodies to study immune cells in cotton rats.
Official title: REAGENTS FOR IMMUNOLOGIC ANALYSIS OF COTTON RAT.
Funded at Sigmovir Biosystems, INC. · NIH-11191835 · Data updated 2026-11-12
This study is all about developing special tools to help scientists see and understand how different immune cells work in cotton rats, which can be really helpful for learning more about diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sigmovir Biosystems, INC. NIH-funded |
| Lab location | 1 site (Rockville, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $598,871 |
| NIH project number | 75N93024C00040-0-9999-1 |
| Project ID | NIH-11191835 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are researchers and scientists working with cotton rat models in immunology and infectious disease studies.
✕Less likely to help
Patients who are not involved in research or do not work with cotton rats will likely not benefit from this research.
What this research studies
This research focuses on creating a diverse set of monoclonal antibodies that will help identify and track different immune cells in cotton rats. The antibodies will be tested for their ability to bind to specific immune targets using advanced techniques like Bio-Layer Interferometry, flow cytometry, ELISA, and Western blot. By providing these tools, the research aims to enhance the understanding of immune responses in cotton rat models, which can be crucial for studying infectious diseases.
Why it matters
Potential benefit: If successful, this research could significantly improve the tools available for studying immune responses in cotton rats, leading to better insights into infectious diseases.
How similar studies have gone: While the development of monoclonal antibodies is a well-established approach, the specific application to cotton rats may present novel opportunities for advancing immunological research.
Where this research is happening
-
Sigmovir Biosystems, INC.
Rockville, United States Active
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.