Developing antibodies to fight certain viruses that can cause pandemics.
Official title: Core D: Antibody Core
Funded at Washington University · NIH-10863695 · Data updated 2026-11-12
This study is looking at how our immune system fights off certain viruses that can be harmful, especially for kids under 11, by creating special antibodies to find out which ones work best, so we can make better vaccines and treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 11, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $5,212,836 |
| NIH project number | 1U19AI181984-01 |
| Project ID | NIH-10863695 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research are children aged 0-11 years who may be at risk for infections from the targeted viruses.
✕Less likely to help
Patients who are older than 11 years or those not at risk for infections from the studied viruses may not receive any benefit from this research.
What this research studies
This research focuses on understanding how the immune system responds to specific viruses that pose significant health risks. By generating large panels of monoclonal antibodies that target the surface proteins of these viruses, the research aims to identify which components of the immune response are most effective. The findings will help in designing vaccines and therapies that can better protect against these viruses, particularly in children under 11 years old. The research involves collaboration with various scientific cores to analyze the structure and function of these antibodies.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective vaccines and treatments for viral infections that currently have no preventative measures.
How similar studies have gone: Previous research has shown success in developing monoclonal antibodies for other viral infections, indicating that this approach has potential for similar breakthroughs.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Ellebedy, Ali Hassan — Washington University
- Study coordinator: Ellebedy, Ali Hassan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.