Developing antibodies to fight bacterial infections

Antibody Core

NIH-funded research Scripps Research Institute, the · NIH-11082426

This study is all about making special proteins called antibodies that can help your body fight off bacterial infections, and it aims to create new treatments that could boost your immune system if you're dealing with these kinds of illnesses.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionScripps Research Institute, the NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11082426 on NIH RePORTER

What this research studies

This research focuses on the engineering and production of antibodies that can target and neutralize bacterial infections. It involves creating both polyclonal and monoclonal antibodies through various methods, including immunization of animals and advanced techniques like single B cell antibody chain sequencing. The antibodies produced will be characterized for their effectiveness in binding to specific bacterial antigens, which is crucial for developing new treatments. Patients may benefit from the resulting therapies that could enhance their immune response against bacterial diseases.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from bacterial infections or those at high risk of such infections.

Not a fit: Patients with viral infections or non-infectious diseases may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new antibody-based therapies that improve treatment outcomes for patients with bacterial infections.

How similar studies have performed: Previous research has shown success in developing antibody therapies for bacterial infections, indicating that this approach has potential for meaningful advancements.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.