Developing antibodies from neotropical primates for biomedical research
Neotropical Primate Reagent Resource
This study is all about using special antibodies from small monkeys to help scientists learn more about diseases and test new treatments that don’t work well in regular lab mice, making it easier to understand how our immune system responds to different health issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-10849272 on NIH RePORTER |
What this research studies
This research focuses on creating specific antibodies from neotropical primates, such as marmosets and squirrel monkeys, to enhance biomedical research. By characterizing the immunoglobulin repertoire of these animals, the project aims to provide essential tools for studying diseases and testing new therapies that cannot be evaluated in traditional rodent models. The antibodies developed will help researchers understand immune responses and disease progression more effectively. This work addresses the current limitations in reagent availability for studying various health conditions.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with conditions that are being studied using neotropical primate models, such as neurodegenerative disorders and infectious diseases.
Not a fit: Patients with conditions that are not represented in the neotropical primate models or those who do not require antibody-based therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the development of therapies and vaccines for diseases that affect humans.
How similar studies have performed: Previous research has shown success in using nonhuman primates as models for various diseases, indicating that this approach has potential for significant advancements.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Engelman, Kathleen — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Engelman, Kathleen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.