Developing and testing vaccines for new infectious diseases
Design and Analysis of Vaccine Trials for Emerging Infectious Disease Threats
This study is all about developing better vaccines to help fight new infectious diseases during outbreaks, especially by vaccinating people who are close to those who are sick, to keep everyone safe and healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10468867 on NIH RePORTER |
What this research studies
This research focuses on creating effective vaccines to combat emerging infectious diseases, particularly in response to outbreaks. It employs innovative trial designs, such as ring vaccination, where individuals in close contact with infected patients are vaccinated to control the spread of disease. The research aims to rigorously evaluate the safety and efficacy of these vaccines in real-world settings, especially during public health emergencies. By addressing the unique challenges faced during outbreaks, the study seeks to improve vaccine development processes and outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals living in or near areas experiencing outbreaks of infectious diseases, particularly those at high risk of exposure.
Not a fit: Patients who are not in outbreak regions or those with pre-existing immunity to the targeted diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the rapid development and deployment of effective vaccines during future infectious disease outbreaks, potentially saving countless lives.
How similar studies have performed: Previous research during the Ebola outbreak has shown that innovative trial designs can successfully evaluate vaccine efficacy, indicating that this approach has potential for success.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Dean, Natalie Exner — Emory University
- Study coordinator: Dean, Natalie Exner
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.