Developing and testing patient-derived cancer models at the University of Pennsylvania
University of Pennsylvania Patient-derived Xenograft Development and Trials Center
This study is working on creating special cancer models from patient tissues to help improve cancer treatments, and it aims to include diverse groups of people in the research to make sure everyone is represented.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10881938 on NIH RePORTER |
What this research studies
This research focuses on creating and utilizing patient-derived xenograft (PDX) models to improve cancer treatment. By developing unique cancer models from patient tissues, the project aims to enhance the translation of scientific discoveries into clinical applications. The research involves collaboration with the PDXNet to ensure effective communication and resource sharing among cancer researchers. Additionally, the project emphasizes diversity and inclusion by ensuring representation of minority groups in the research process.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who are seeking innovative treatment options and are willing to contribute their tissue samples for model development.
Not a fit: Patients with non-cancerous conditions or those not interested in participating in tissue donation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments for patients.
How similar studies have performed: Previous research has shown success in using patient-derived xenograft models to advance cancer treatment, indicating a promising approach.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Carroll, Martin — University of Pennsylvania
- Study coordinator: Carroll, Martin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.