Developing advanced tools for studying autoimmune diseases using genome engineering.
Genome Engineering Core
This study is all about using advanced gene-editing tools to create special mice and cells that help scientists learn more about inflammatory and autoimmune diseases, with the hope that this research will lead to better treatments for patients like you.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10925279 on NIH RePORTER |
What this research studies
The Genome Engineering Core at Washington University focuses on providing researchers with access to cutting-edge genomic technologies to create models for studying inflammatory and autoimmune diseases. This involves using techniques like CRISPR/Cas9 to edit genes in cells and animals, allowing for a better understanding of how genetic changes affect disease processes. By developing genetically-engineered mice and induced pluripotent stem cells, the core aims to facilitate pre-clinical testing and functional analysis of these diseases. Patients may benefit from the insights gained through these innovative models, which could lead to new treatments and therapies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are individuals with autoimmune diseases or those at risk for developing such conditions.
Not a fit: Patients with non-autoimmune conditions or those not involved in genetic research may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating autoimmune diseases.
How similar studies have performed: Other research utilizing CRISPR technology has shown promising results in genetic editing and modeling diseases, indicating a strong potential for success in this area.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Cooper, Megan Anne — Washington University
- Study coordinator: Cooper, Megan Anne
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.