Developing advanced tools for precise brain circuit control
Official title: Artifact-free Micro-LED Optoelectrode for Multi-color Neuromodulation
Funded at University of Michigan at Ann Arbor · NIH-11103986 · Data updated 2026-11-12
This study is working on new tiny devices that use light to help scientists see and control brain activity better, which could lead to better treatments for people with neurological disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | June 1, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $556,525 |
| NIH project number | 1R01NS142069-01 |
| Project ID | NIH-11103986 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with neurological disorders that affect brain circuit function.
✕Less likely to help
Patients with conditions unrelated to brain circuit dysfunction may not receive any benefit from this research.
What this research studies
This research focuses on creating innovative micro-LED optoelectrodes that allow for precise monitoring and manipulation of brain circuits in real-time. By integrating tiny light-emitting diodes with recording devices, the project aims to enhance our understanding of how specific neurons interact within local brain circuits. The approach involves designing and testing these advanced tools to achieve high-density recordings and targeted stimulation of neurons, which could lead to breakthroughs in neuromodulation techniques. Patients may benefit from improved treatments for neurological disorders as a result of this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for neurological conditions by enabling precise control of brain circuits.
How similar studies have gone: Previous research in optogenetics has shown promising results in manipulating neural circuits, suggesting that this approach could lead to significant advancements in the field.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Yoon, Euisik — University of Michigan at Ann Arbor
- Study coordinator: Yoon, Euisik
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.