Developing advanced therapies for cartilage regeneration to improve joint function
Official title: CReATE Motion Center: Cartilage Regeneration using Advanced Technologies to Enable Motion
Funded at Philadelphia VA Medical Center · NIH-11175325 · Data updated 2026-11-12
This study is all about creating a new center at the VA Medical Center in Philadelphia that will focus on developing new treatments to help people with arthritis and joint injuries feel better and move more easily.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Philadelphia VA Medical Center NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| NIH project number | 5I50RX004845-02 |
| Project ID | NIH-11175325 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are individuals with arthritis, joint injuries, or related joint disorders who are seeking innovative treatment options.
✕Less likely to help
Patients with conditions unrelated to cartilage or joint issues may not receive any benefit from this research.
What this research studies
This research focuses on establishing a new center dedicated to cartilage regeneration at the Corporal Michael J. Crescenz VA Medical Center in Philadelphia. The center aims to develop innovative therapies that utilize advanced technologies and cell-based interventions to treat arthritis and joint injuries. By leveraging expertise from various medical and engineering fields, the project seeks to create a translational pipeline that accelerates the implementation of these therapies into clinical practice, ultimately enhancing joint function and quality of life for patients. Collaboration with other institutions, such as Emory University, will further enrich the research efforts.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve joint function and reduce pain for patients suffering from arthritis and related conditions.
How similar studies have gone: Previous research in cartilage regeneration and cell-based therapies has shown promising results, indicating potential for success in this novel approach.
Where this research is happening
-
Philadelphia VA Medical Center
Philadelphia, United States Active
Researchers
- Principal investigator: Mauck, Robert L — Philadelphia VA Medical Center
- Study coordinator: Mauck, Robert L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.