Developing advanced tests for monitoring Type 1 diabetes in children
Official title: Robust Mass Spectrometric Protein/Peptide Assays for Type 1 Diabetes Clinical Applications
Funded at Battelle Pacific Northwest Laboratories · NIH-10891667 · Data updated 2026-11-12
This study is working on new, more accurate tests to measure important proteins and hormones in kids and young adults with Type 1 diabetes, so doctors can better track how the disease is progressing and how well treatments are working.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Pacific Northwest Laboratories NIH-funded |
| Lab location | 1 site (Richland, United States) |
| Project start | July 21, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $949,078 |
| NIH project number | 5U01DK137113-02 |
| Project ID | NIH-10891667 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children and young adults diagnosed with Type 1 diabetes.
✕Less likely to help
Patients with Type 2 diabetes or other forms of diabetes may not benefit from this research.
What this research studies
This research focuses on creating reliable tests that measure specific proteins and hormones related to Type 1 diabetes (T1D) in children and young adults. By using advanced mass spectrometry techniques, the project aims to develop assays that can accurately track disease progression and the effectiveness of treatments. These tests will provide crucial information about the body's insulin and glucagon levels, helping healthcare providers make informed decisions about patient care. The goal is to improve monitoring methods that currently rely heavily on less precise antibody-based tests.
Why it matters
Potential benefit: If successful, this research could lead to more accurate monitoring of Type 1 diabetes, allowing for better management and treatment options for affected children.
How similar studies have gone: Previous research has shown promise in using mass spectrometry for similar applications, indicating potential for success in this novel approach.
Where this research is happening
-
Battelle Pacific Northwest Laboratories
Richland, United States Active
Researchers
- Principal investigator: Qian, Wei-Jun — Battelle Pacific Northwest Laboratories
- Study coordinator: Qian, Wei-Jun
Related research
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-
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A UK study tests two different approaches to help adults with type 1 diabetes recognize and respond to low blood sugar by comparing a high-tech insulin system with targeted education.
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Researchers are studying how the surrounding tissue of the pancreas and its proteins influence insulin-producing cells in people with type 1 diabetes.
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Understanding how hypoglycemia awareness changes in adults with type 1 diabetes and how automated insulin delivery and exercise might help restore it
This study will look at adults with type 1 diabetes to see how their awareness of low blood sugar evolves over time and whether automated insulin delivery and high-intensity exercise can help restore that awareness.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.