NIH-funded research Sbir 2 grant

Developing advanced technology for studying brain activity

Official title: Commercialization of integrated electrode-electronics system for large scale, long-lasting electrophysiology

Funded at Spikegadgets, LLC · NIH-10897943 · Data updated 2026-11-12

This study is working on a new tool that can safely and effectively track the activity of many brain cells in rodents, which could help us learn more about how the brain works and improve technology for studying brain health.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionSpikegadgets, LLC
NIH-funded
Lab location1 site (San Francisco, UNITED STATES)
Project startJuly 1, 2022
Project endJune 30, 2025
Funding year2024
Award (this year)$652,837
NIH project number5R44NS127692-03
Project IDNIH-10897943 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research would include individuals with acquired brain injuries or those interested in advancements in neurotechnology.

Less likely to help

Patients with conditions unrelated to brain function or those not involved in research settings may not receive any benefit from this research.

What this research studies

This research focuses on creating a new type of electrode-electronics system that can monitor the activity of thousands of neurons in the brain, specifically in rodent models. By utilizing flexible polyimide-based probes and advanced data logging electronics, the project aims to enhance the recording capabilities of brain activity while minimizing damage to brain tissue. This technology is designed to provide long-lasting and stable recordings, which could lead to better understanding of brain functions and behaviors. The research is part of a broader initiative to improve neurotechnology for scientific applications.

Why it matters

Potential benefit: If successful, this research could lead to significant advancements in understanding brain function and behavior, potentially benefiting future treatments for brain injuries.

How similar studies have gone: Other research has shown success with similar neurotechnology approaches, indicating a promising avenue for further exploration.

Where this research is happening

  • Spikegadgets, LLC
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Karlsson, Mattias Peter — Spikegadgets, LLC
  • Study coordinator: Karlsson, Mattias Peter

Related research

Other NIH-funded projects on the same topics.

  • A platform for advanced brain activity monitoring

    This study is working on a new technology that will help scientists better understand brain activity by creating a special device with many tiny sensors, making it easier to study how the brain works in different animals and situations.

    NIH research Spikegadgets, LLC · San Francisco, UNITED STATES · NIH-10921067

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.