Developing advanced technologies to study how cells respond to mechanical forces.
Official title: Center on Probes for Molecular Mechanotechnology
Funded at Emory University · NIH-10904654 · Data updated 2026-11-12
This study is all about figuring out how living cells feel and react to different forces around them, which could help us understand diseases that involve cell movement and behavior better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | August 10, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $1,077,182 |
| NIH project number | 5RM1GM145394-02 |
| Project ID | NIH-10904654 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve abnormal cell behavior or mechanotransduction pathways, such as certain cancers or cardiovascular diseases.
✕Less likely to help
Patients with conditions unrelated to cellular mechanics or those who do not have access to the required technologies may not benefit from this research.
What this research studies
This research focuses on creating innovative tools to explore how living cells sense and respond to mechanical forces, a field known as mechanobiology. The project involves developing high-resolution probes that can measure forces at the molecular level and tagging cells based on their mechanical interactions. By using advanced imaging techniques and flow cytometry, researchers aim to gain insights into cellular behavior and the role of mechanical signals in various biological processes. This work could lead to a better understanding of diseases related to cell mechanics.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of cellular responses to mechanical forces, potentially leading to new treatments for diseases linked to cell mechanics.
How similar studies have gone: Other research has shown promise in mechanobiology, indicating that this approach could lead to significant advancements in understanding cellular functions.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Salaita, Khalid S. — Emory University
- Study coordinator: Salaita, Khalid S.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.