Developing advanced techniques to measure important metabolites in the body
Down Field Spectroscopy at Ultrahigh Fields
This study is exploring new ways to use special imaging technology to measure important substances in the body that can help us understand diseases related to aging and brain health, so patients can get better diagnoses and insights into their conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11123511 on NIH RePORTER |
What this research studies
This research focuses on creating innovative magnetic resonance spectroscopy technologies to measure key metabolites like NAD+, Glutamine, and ATP that are crucial for understanding various diseases. By utilizing advanced techniques such as spectral selective excitation and optimized pulse sequences, the research aims to provide insights into conditions related to aging, neurodegeneration, and mitochondrial diseases. Patients may benefit from improved diagnostic methods and a better understanding of their conditions through these novel technologies.
Who could benefit from this research
Good fit: Ideal candidates include individuals experiencing symptoms related to aging, neurodegeneration, or mitochondrial diseases.
Not a fit: Patients with conditions unrelated to the metabolites being studied may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to enhanced diagnostic capabilities for age-related and neurodegenerative diseases.
How similar studies have performed: Previous research has shown promise in using advanced spectroscopy techniques for metabolic analysis, indicating potential success for this novel approach.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Witschey, Walter R.t. — University of Pennsylvania
- Study coordinator: Witschey, Walter R.t.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.