Developing advanced techniques to analyze RNA modifications
Development of Next-Generation Mass Spectrometry-based de novo RNA Sequencing for all Modifications
['FUNDING_R01'] · STATE UNIVERSITY OF NEW YORK AT ALBANY · NIH-11012884
This study is working on a new way to analyze RNA, which could help us better understand how changes in RNA are linked to diseases like breast cancer, type-2 diabetes, and obesity, ultimately benefiting patients by providing more insights into their conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STATE UNIVERSITY OF NEW YORK AT ALBANY (nih funded) |
| Locations | 1 site (ALBANY, UNITED STATES) |
| Trial ID | NIH-11012884 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a new mass spectrometry method to accurately sequence RNA and identify all its modifications. By addressing the limitations of current technologies, this project aims to provide a comprehensive understanding of RNA sequences, which is crucial for understanding various diseases. Patients may benefit from insights gained about RNA modifications related to conditions like breast cancer, type-2 diabetes, and obesity. The approach involves advanced analytical techniques to ensure that all modifications are detected and characterized.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by diseases such as breast cancer, type-2 diabetes, or obesity.
Not a fit: Patients with conditions unrelated to RNA modifications may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for diseases linked to RNA modifications.
How similar studies have performed: While mass spectrometry has been used in related fields, this specific approach to RNA modifications is novel and has not been extensively tested.
Where this research is happening
ALBANY, UNITED STATES
- STATE UNIVERSITY OF NEW YORK AT ALBANY — ALBANY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHANG, SHENGLONG — STATE UNIVERSITY OF NEW YORK AT ALBANY
- Study coordinator: ZHANG, SHENGLONG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus