Developing advanced sutures to prevent blood clots in microvascular surgery
Ultra-thin, high strength, drug-eluting sutures for prevention of thrombosis in microvascular surgery
['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-10895430
This study is testing new super-thin stitches that can release medicine to help prevent blood clots during small surgeries, making recovery easier and safer for patients who have had trauma or cancer treatment.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10895430 on ClinicalTrials.gov |
What this research studies
This research focuses on creating ultra-thin, high-strength sutures that release medication to prevent thrombosis during microvascular surgeries, which are often performed to repair tissue after trauma or cancer. The sutures will deliver anticoagulant drugs directly at the surgical site, minimizing the risk of blood clots that can lead to complications and re-operations. By improving the effectiveness of these sutures, the research aims to enhance patient outcomes and reduce healthcare costs associated with surgical failures. The approach is designed to integrate seamlessly into existing surgical practices without requiring additional procedures.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing microvascular surgeries, such as tissue transplantation or reattachment of amputated parts.
Not a fit: Patients who are not undergoing microvascular surgeries or those with contraindications to anticoagulant therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of thrombosis-related complications in microvascular surgeries, leading to better recovery outcomes for patients.
How similar studies have performed: Previous research has shown promise in using drug-eluting materials in surgical applications, suggesting that this approach could be effective.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PARIKH, KUNAL SAILESH — JOHNS HOPKINS UNIVERSITY
- Study coordinator: PARIKH, KUNAL SAILESH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.