Developing advanced sensors to record electrical signals in cells.
Three-dimensional field effect transistor arrays as a platform technology for intracellular electrophysiology recording.
This study is working on a new gadget that can pick up tiny electrical signals from cells really well, which could help us learn more about how cells work and how conditions like Alzheimer's and epilepsy affect them, making it easier to gather important information over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11071717 on NIH RePORTER |
What this research studies
This research focuses on creating a new type of electronic interface that can record electrical signals from cells with high precision. By using three-dimensional field effect transistor arrays, the project aims to improve our understanding of how ions move through cell membranes, which is crucial for understanding diseases like Alzheimer's and epilepsy. The innovative design of these sensors allows them to integrate more naturally with biological tissues, leading to better data collection over longer periods. This approach could provide insights into cellular behaviors that are currently difficult to measure accurately.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological conditions such as Alzheimer's disease or epilepsy.
Not a fit: Patients with conditions unrelated to cellular signaling or those who do not have neurological disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for neurological diseases by enhancing our understanding of cellular signaling.
How similar studies have performed: Previous research has shown promise in using advanced sensor technologies for cellular studies, indicating potential for success in this novel approach.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Xu, Sheng — University of California, San Diego
- Study coordinator: Xu, Sheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.