Developing advanced probes for detailed brain imaging in humans
Toward functional molecular neuroimaging using vasoactive probes in human subjects
This study is working on new tools to help doctors see how the brain works in real-time, using special probes that make brain imaging clearer and more detailed, so they can better understand brain activity and health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Institute of Technology NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-10906791 on NIH RePORTER |
What this research studies
This research focuses on creating innovative chemical probes that enhance the ability to monitor brain function with high precision. By integrating these probes with imaging techniques like MRI, the study aims to provide detailed insights into dynamic brain processes in a noninvasive manner. The probes are designed to improve the detection of neurotransmitters and other molecular species, allowing for a more comprehensive understanding of neurobiological phenomena across the brain. This approach seeks to overcome the limitations of current imaging methods by offering better sensitivity and resolution.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with neurological conditions or those interested in understanding brain function, particularly in relation to neurotransmitter activity.
Not a fit: Patients with severe cognitive impairments or those unable to undergo MRI or similar imaging procedures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding brain function and disorders, potentially improving diagnosis and treatment options for various neurological conditions.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques for brain studies, but the specific approach of using vasoprobes is relatively novel and untested.
Where this research is happening
Cambridge, United States
- Massachusetts Institute of Technology — Cambridge, United States (Active)
Researchers
- Principal investigator: Jasanoff, Alan — Massachusetts Institute of Technology
- Study coordinator: Jasanoff, Alan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.