Developing advanced optical techniques to control brain activity
Mesoscale bidirectional two-photon holographic optogenetics
This study is exploring a new way to use light to carefully control brain activity, which could help scientists learn more about how our brains process sensations and actions, and it’s aimed at anyone interested in understanding brain function better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-10516934 on NIH RePORTER |
What this research studies
This research focuses on creating a new optical technology that allows scientists to manipulate brain activity with high precision. By using a two-photon holographic approach, the team aims to control the activity of large groups of neurons simultaneously, which could help in understanding how the brain processes information related to sensation and action. The methodology involves building specialized microscopes and tools that can target specific neurons and measure their responses in real-time. This innovative approach could lead to breakthroughs in how we understand brain function and its relation to behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with neurological conditions that affect cognition and behavior, as well as those interested in advancements in brain research.
Not a fit: Patients with conditions unrelated to brain function or those who do not have access to the research facilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for neurological disorders by providing insights into brain function and improving our ability to manipulate neural circuits.
How similar studies have performed: While the approach is innovative, similar techniques in optogenetics have shown promise in other studies, indicating potential for success in this novel application.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Adesnik, Hillel — University of California Berkeley
- Study coordinator: Adesnik, Hillel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.