Developing advanced MRI technology to identify early signs of Alzheimer's disease
Official title: ADVANCED COMPREHENSIVE MAGNETIC RESONANCE SOLUTION FOR THE NONINVASIVE CHARACTERIZATION OF HIGH RESOLUTION METABOLIC BIOMARKERS OF RISK IN PATIENTS WITH ALZHEIMER'S DISEASE AND DEMENTIA
Funded at Advanced Imaging Research, INC. · NIH-11130773 · Data updated 2026-11-12
This study is testing a new technology that improves brain scans to help find early signs of Alzheimer's disease, so patients can get diagnosed sooner and manage their condition better.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Advanced Imaging Research, INC. NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | September 20, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,275,000 |
| NIH project number | 4R44AG085817-02 |
| Project ID | NIH-11130773 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for Alzheimer's disease, including those with a family history or early cognitive symptoms.
✕Less likely to help
Patients with advanced Alzheimer's disease or those who do not exhibit any risk factors for the disease may not benefit from this research.
What this research studies
This research focuses on creating a cutting-edge hardware-software system called ADRD360 that enhances magnetic resonance imaging (MRI) and spectroscopy (MRS) to detect metabolic biomarkers associated with Alzheimer's disease and related dementias. By improving the resolution of brain imaging, the project aims to identify early indicators of Alzheimer's risk, which could lead to timely interventions. The approach involves optimizing radio-frequency coils and imaging techniques to achieve unprecedented clarity in brain scans. Patients may benefit from earlier diagnosis and better management of their condition through this innovative technology.
Why it matters
Potential benefit: If successful, this research could enable earlier detection of Alzheimer's disease, allowing for timely treatment and improved patient outcomes.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for early detection of Alzheimer's, suggesting that this approach could build on existing knowledge.
Where this research is happening
-
Advanced Imaging Research, INC.
Cleveland, United States Active
Researchers
- Principal investigator: Srinivasan, Ravi — Advanced Imaging Research, INC.
- Study coordinator: Srinivasan, Ravi
Related research
Other NIH-funded projects on the same topics.
-
Global picture of dementia risk and memory loss across the world
A large international effort gathers data from many studies to understand how dementia and memory problems develop around the world, using shared information to reveal patterns and risk factors.
-
Automated language analysis for Alzheimer’s disease and frontotemporal dementia in Latino and English speakers
A low-cost, automated speech and language analysis tool is being developed to help identify Alzheimer’s disease or frontotemporal dementia in Latino and English-speaking people.
-
Automated language analysis for Alzheimer’s and frontotemporal dementia across Latino and English-speaking groups
A low-cost, automated language study aims to help diagnose and understand Alzheimer’s and FTD in diverse Spanish- and English-speaking communities.
-
Automated language analysis to help diagnose Alzheimer’s and frontotemporal dementia in Latino and English speakers
A low-cost, computer-based method analyzes speech and language to help identify Alzheimer’s disease or frontotemporal dementia in Latino and English-speaking people.
-
Automated language analysis for Alzheimer's and frontotemporal dementia in Latino and English-speaking communities
A low-cost, computer-based language analysis method is being developed to help identify Alzheimer’s disease and frontotemporal dementia in Latino and English-speaking people.
-
Automated language analysis to detect Alzheimer’s and frontotemporal dementia in Latino and English-speaking adults
A low-cost, computer-based language and speech analysis tool will help identify Alzheimer’s disease and frontotemporal dementia in Latino and English-speaking adults.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.