Developing advanced MRI techniques to measure brain health
TRD1: Quantitative Imaging of Physiological Markers
['FUNDING_OTHER'] · HUGO W. MOSER RES INST KENNEDY KRIEGER · NIH-11112350
This study is working on new MRI methods to get clearer pictures of how your brain is working, especially for people with Alzheimer's, by looking at important things like blood flow and oxygen levels, so we can better understand brain health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HUGO W. MOSER RES INST KENNEDY KRIEGER (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11112350 on ClinicalTrials.gov |
What this research studies
This research focuses on creating innovative MRI techniques that provide detailed and interpretable measurements of brain physiology. It aims to assess key parameters such as cerebral blood flow, oxygen extraction, and blood-brain barrier permeability, which are crucial for understanding brain health, particularly in conditions like Alzheimer's disease. The study will utilize advanced imaging methods and deep learning to enhance the speed and accuracy of these measurements, making them clinically applicable. By integrating various imaging techniques, the research seeks to provide a comprehensive view of brain function and structure.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or those exhibiting early signs of cognitive decline.
Not a fit: Patients with non-neurological conditions or those who do not have any cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools for early detection and monitoring of Alzheimer's disease and other neurological conditions.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for assessing brain health, indicating that this approach could yield valuable insights.
Where this research is happening
BALTIMORE, UNITED STATES
- HUGO W. MOSER RES INST KENNEDY KRIEGER — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LU, HANZHANG — HUGO W. MOSER RES INST KENNEDY KRIEGER
- Study coordinator: LU, HANZHANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease