Developing advanced mouse models to better understand human diseases
Bioinformatics Section
This study is working on developing special mouse models that closely mimic human diseases to help researchers better understand how these diseases develop and find new ways to treat them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jackson Laboratory NIH-funded |
| Lab location | 1 site (Bar Harbor, United States) |
| Project ID | NIH-10904724 on NIH RePORTER |
What this research studies
This research focuses on creating innovative mouse models that accurately reflect the complexity of human diseases. By integrating genetic, genomic, and phenotypic data, the project aims to enhance our understanding of how various factors contribute to disease development. The Bioinformatics Core at The Jackson Laboratory will utilize a range of tools and databases to refine these models, ensuring they are more representative of human conditions. This approach will help researchers identify disease variants and improve the annotation of phenotypes, ultimately leading to better insights into disease mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with complex genetic conditions that may benefit from insights gained through advanced animal models.
Not a fit: Patients with straightforward, single-gene disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and therapies for patients by providing a deeper understanding of disease mechanisms.
How similar studies have performed: Previous research has shown success in using advanced animal models to better understand complex diseases, indicating that this approach is promising.
Where this research is happening
Bar Harbor, United States
- Jackson Laboratory — Bar Harbor, United States (Active)
Researchers
- Principal investigator: Chesler, Elissa J — Jackson Laboratory
- Study coordinator: Chesler, Elissa J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.