Developing advanced microscopy techniques to discover new cancer treatments
Official title: High-throughput high-resolution microscopy for phenotypic drug discovery applications
Funded at University of Toledo · NIH-10654145 · Data updated 2026-11-12
This study is working on a new tool that helps scientists see how cancer drugs kill cancer cells in real time, which could lead to better treatments for patients with tough-to-treat cancers.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Toledo NIH-funded |
| Lab location | 1 site (Toledo, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $451,500 |
| NIH project number | 1R15EB034552-01 |
| Project ID | NIH-10654145 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with cancers that exhibit multidrug resistance and have limited treatment options.
✕Less likely to help
Patients with non-cancerous conditions or those whose cancers are not resistant to current therapies may not benefit from this research.
What this research studies
This research focuses on overcoming multidrug resistance (MDR) in cancer treatment by developing a new high-resolution microscopy tool that can identify how drugs kill cancer cells in real time. By utilizing advanced imaging techniques and artificial intelligence, the project aims to streamline the drug discovery process, making it faster and more efficient. Patients may benefit from new therapies that target resistant cancer cells more effectively, potentially leading to better treatment outcomes. The research will explore various mechanisms of cell death to find innovative ways to combat aggressive cancers.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective cancer treatments that overcome drug resistance.
How similar studies have gone: Other research has shown promise in using advanced imaging and AI for drug discovery, indicating that this approach could be effective.
Where this research is happening
-
University of Toledo
Toledo, United States Active
Researchers
- Principal investigator: Ray, Aniruddha — University of Toledo
- Study coordinator: Ray, Aniruddha
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.