Developing advanced microscopy techniques for faster cancer drug discovery
High-throughput high-resolution microscopy for phenotypic drug discovery applications
This study is working on a special microscope to help scientists see how cancer cells die, which could lead to faster discoveries of new cancer treatments, and it also aims to teach college students from diverse backgrounds how to use these cool new tools.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Toledo NIH-funded |
| Lab location | 1 site (Toledo, United States) |
| Project ID | NIH-11039609 on NIH RePORTER |
What this research studies
This research focuses on creating a new type of microscope that combines high-resolution imaging with advanced techniques to better understand how cancer cells die. By observing both the physical and chemical changes in live cells, the project aims to speed up the process of discovering new anti-cancer drugs, which traditionally takes many years. The researchers will enhance existing holographic microscopy technology and integrate it with tumor-on-chip models to personalize therapy assessments. Additionally, the project emphasizes training undergraduate students, especially from underrepresented backgrounds, in these advanced techniques.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who may benefit from new anti-cancer therapies developed through this innovative approach.
Not a fit: Patients with conditions unrelated to cancer or those who have already exhausted all available treatment options may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective cancer treatments by improving the drug discovery process.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques for drug discovery, indicating that this approach could be effective.
Where this research is happening
Toledo, United States
- University of Toledo — Toledo, United States (Active)
Researchers
- Principal investigator: Ray, Aniruddha — University of Toledo
- Study coordinator: Ray, Aniruddha
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.