Developing advanced microendoscopes for real-time imaging of cells and tissues
Official title: TR&D2
Funded at University of Michigan at Ann Arbor · NIH-11094975 · Data updated 2026-11-12
This study is working on new tiny cameras that can take detailed pictures of your body's tissues in real-time, helping doctors and researchers see how cells behave and interact, which is important for understanding diseases better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | May 16, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $271,109 |
| NIH project number | 1P41EB035084-01A1 |
| Project ID | NIH-11094975 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with conditions affecting the oral cavity or pancreas, where detailed imaging is necessary for diagnosis and treatment.
✕Less likely to help
Patients with conditions that do not involve the oral cavity or pancreas may not benefit from this research.
What this research studies
This research focuses on creating innovative fiber-coupled microendoscopes that allow for real-time imaging of biological tissues at a sub-cellular level. By utilizing various optical configurations, these microendoscopes aim to provide flexibility for both pre-clinical and clinical applications. The project will develop first and second-generation instruments, with advanced scanning mechanisms to capture detailed images of internal organs, including challenging areas like the oral cavity and pancreas. This technology will enable researchers to observe cellular behaviors and interactions in vivo, which is crucial for understanding disease progression.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic capabilities and treatment monitoring for various diseases, particularly cancers.
How similar studies have gone: Other research has shown promise in using advanced imaging techniques for cellular observation, indicating that this approach could be effective.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Wang, Thomas D — University of Michigan at Ann Arbor
- Study coordinator: Wang, Thomas D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.