Developing advanced imaging techniques to study cancer spread in zebrafish
Technical Development Unit 1: Intelligent live imaging of metastasis patterns and subcellular molecular states at the whole organism level
This study is working on a special microscope to help scientists see how cancer cells move and change in zebrafish, which could help us learn more about cancer spread and find better ways to treat it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10903848 on NIH RePORTER |
What this research studies
This research focuses on creating a new type of microscope that can image cancer cells in zebrafish at both the whole organism and subcellular levels. By using a transparent zebrafish model, researchers aim to understand how cancer cells behave and adapt as they spread throughout the body. The project combines advanced imaging technology with computational methods to automatically identify and analyze metastatic sites, providing insights into cancer cell characteristics and behaviors. This innovative approach could lead to a better understanding of cancer metastasis and potentially improve treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cancer, particularly those whose cancer has a known tendency to metastasize.
Not a fit: Patients with non-cancerous conditions or those whose cancer is not metastatic may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding cancer metastasis, ultimately improving treatment options for patients with cancer.
How similar studies have performed: Previous research using advanced imaging techniques in animal models has shown promise in understanding cancer biology, suggesting that this approach could yield valuable insights.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Fiolka, Reto Paul — Ut Southwestern Medical Center
- Study coordinator: Fiolka, Reto Paul
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.