Developing advanced imaging techniques to study cancer cell behavior
Research Test-Bed Unit
['FUNDING_OTHER'] · NORTHWESTERN UNIVERSITY · NIH-11003289
This study is looking at how cancer cells, especially in ovarian cancer, change and survive chemotherapy, with the hope of finding better ways to treat these tough cells and help patients feel better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHWESTERN UNIVERSITY (nih funded) |
| Locations | 1 site (Chicago, UNITED STATES) |
| Trial ID | NIH-11003289 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a new imaging platform to analyze the structure and function of chromatin in cancer cells, particularly in ovarian cancer. By examining how cancer stem cells adapt and resist chemotherapy, the research aims to uncover the underlying mechanisms that contribute to tumor growth and recurrence. Patients may benefit from insights gained through this research, which could lead to improved treatment strategies targeting these resilient cancer cells. The project will involve collecting and analyzing various cell and tissue samples to enhance the imaging technology's effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with ovarian cancer, particularly those experiencing chemotherapy resistance.
Not a fit: Patients with non-cancerous conditions or those not diagnosed with ovarian cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for ovarian cancer by targeting the mechanisms that allow cancer stem cells to survive chemotherapy.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to study cancer biology, indicating potential for success in this novel approach.
Where this research is happening
Chicago, UNITED STATES
- NORTHWESTERN UNIVERSITY — Chicago, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MATEI, DANIELA E — NORTHWESTERN UNIVERSITY
- Study coordinator: MATEI, DANIELA E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.