Developing advanced imaging techniques to identify cell types in the human brain.
Scalable 3D molecular imaging and data analysis for cell census generation
This study is exploring new ways to take detailed 3D pictures of different cell types in the human brain, especially in the area responsible for our sense of smell, to help us better understand brain structure and potentially improve treatments for neurological conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arizona State University-Tempe Campus NIH-funded |
| Lab location | 1 site (Tempe, United States) |
| Project ID | NIH-10369885 on NIH RePORTER |
What this research studies
This research focuses on creating innovative 3D molecular imaging methods to identify different cell types within human brain tissue, specifically targeting the olfactory system. By utilizing advanced microscopy techniques, the project aims to generate a detailed atlas of the human brain, mapping connections between the olfactory epithelium and the olfactory bulb. The approach involves imaging proteins and RNA to enhance our understanding of brain cell composition and organization. Patients may benefit from insights gained that could inform future treatments for neurological conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions affecting the olfactory system or those interested in contributing to advancements in brain research.
Not a fit: Patients with conditions unrelated to the olfactory system or those not seeking participation in research may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of brain cell types and their functions, potentially improving treatments for neurological disorders.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques for brain mapping, indicating a potential for success in this novel approach.
Where this research is happening
Tempe, United States
- Arizona State University-Tempe Campus — Tempe, United States (Active)
Researchers
- Principal investigator: Shepherd, Douglas — Arizona State University-Tempe Campus
- Study coordinator: Shepherd, Douglas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.