Developing advanced imaging for treating liver tumors with histotripsy
Advanced C-arm imaging platform for histotripsy treatment of liver tumors
This study is testing a new way to treat liver tumors using advanced imaging technology to help doctors see and target the tumors better, making the treatment safer and more effective for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10991401 on NIH RePORTER |
What this research studies
This research aims to enhance the treatment of liver tumors using a new imaging platform that combines C-arm technology with histotripsy, a noninvasive method for tumor ablation. The approach focuses on improving the visualization and targeting of tumors, which is crucial for effective treatment. By utilizing C-arm x-ray fluoroscopy and cone-beam CT, the researchers hope to overcome the limitations of current imaging methods, making the treatment more precise and accessible. This innovative platform is designed to facilitate better planning and assessment of histotripsy procedures, potentially leading to improved patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with liver tumors who are seeking noninvasive treatment options.
Not a fit: Patients with tumors that are not amenable to histotripsy or those who do not meet specific eligibility criteria for the treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a more effective and less invasive treatment option for patients with liver tumors.
How similar studies have performed: Previous studies have shown promise for histotripsy in animal models, indicating potential for success in human applications, although this specific imaging approach is novel.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Laeseke, Paul F — University of Wisconsin-Madison
- Study coordinator: Laeseke, Paul F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.