Developing advanced heart assist devices for children with heart failure
Multifunctional VAD Technology for High-Risk Pediatric Patients
This study is working on new heart devices for kids with serious heart problems to help them get better blood flow and avoid complications, making sure these devices are safe and fit their special needs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Drexel University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10655485 on NIH RePORTER |
What this research studies
This research focuses on creating innovative ventricular assist devices (VADs) specifically designed for high-risk pediatric patients suffering from heart failure due to congenital or acquired heart disease. The project aims to address the limitations of current VAD technologies, which often do not meet the unique physiological needs of children. By developing a hybrid-design, magnetically levitated device, the research seeks to improve blood flow and reduce complications such as blood cell damage and clotting. This approach involves advanced engineering and clinical collaboration to ensure the devices are safe and effective for young patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are pediatric patients with heart failure, particularly those with congenital heart defects or other serious cardiovascular conditions.
Not a fit: Patients with stable heart conditions or those who do not require mechanical support for their heart may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a life-saving treatment option for children with severe heart failure who currently have limited therapeutic choices.
How similar studies have performed: While there have been advancements in adult VAD technologies, this research aims to pioneer a novel approach specifically tailored for pediatric patients, addressing a significant unmet clinical need.
Where this research is happening
Philadelphia, United States
- Drexel University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Throckmorton, Amy — Drexel University
- Study coordinator: Throckmorton, Amy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.