Developing advanced data analysis methods for understanding heart cell types and gene expression.
Data Analysis Core
This study is working on new ways to understand heart tissues better by combining different types of biological data, which will help researchers identify various cell types and where they are located in the heart, ultimately benefiting people with heart conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10877086 on NIH RePORTER |
What this research studies
This research focuses on creating robust computational methods to analyze and integrate complex biological data, particularly related to heart tissues. It involves a systematic approach divided into four tiers, where each tier enhances the integration of data from various sources. The team will utilize both public and proprietary software tools to manage and analyze data, aiming to identify different cell types and their spatial distribution in the heart. By collaborating with other tissue mapping centers, the project seeks to ensure comprehensive data management and analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with heart conditions or those interested in the genetic and cellular basis of heart health.
Not a fit: Patients without heart conditions or those not interested in genetic research may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of heart cell types and their functions, potentially informing new treatments for heart diseases.
How similar studies have performed: Previous research utilizing advanced computational methods for genomic data analysis has shown promise in enhancing our understanding of complex biological systems.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Tan, Kai — Children's Hosp of Philadelphia
- Study coordinator: Tan, Kai
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.