NIH-funded research NIH-funded research

Developing advanced computer models to predict health outcomes.

Official title: Computational Modeling Core

Funded at Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · NIH-11091667 · Data updated 2026-11-12

This study is looking at how blood infections from a fungus called Candida albicans work, using advanced computer models to better understand them, so that patients can receive more personalized and effective treatments.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionLundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
NIH-funded
Lab location1 site (Torrance, United States)
Project startAugust 10, 2023
Project endMay 31, 2028
Funding year2025
Award (this year)$224,570
NIH project number5U19AI172713-03
Project IDNIH-11091667 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals experiencing bloodstream infections, particularly those caused by Candida albicans.

Less likely to help

Patients with infections not related to Candida albicans or those who do not have bloodstream infections may not benefit from this research.

What this research studies

This research focuses on creating sophisticated computational models that analyze and predict physiological processes related to blood infections, particularly those caused by Candida albicans. By integrating various types of biological data and using machine learning techniques, the project aims to enhance our understanding of how these infections develop and respond to treatments. Patients may benefit from improved predictive tools that can lead to more effective treatment strategies tailored to individual needs.

Why it matters

Potential benefit: If successful, this research could lead to more accurate predictions of infection outcomes and personalized treatment plans for patients.

How similar studies have gone: Previous research has shown promise in using computational modeling for predicting health outcomes, indicating that this approach could be effective.

Where this research is happening

  • Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
    Torrance, United States
    Active

Researchers

  • Principal investigator: Meyer, Aaron Samuel — Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
  • Study coordinator: Meyer, Aaron Samuel

Related research

Other NIH-funded projects on the same topics.

  • Immunometabolic and epigenetic changes in the mouth’s immunity in diabetes-related thrush

    This grant looks at why people with diabetes get a higher risk of oral thrush and how high blood sugar affects the mouth’s defenses against Candida albicans.

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    A short, patient-friendly study will explore how a nerve-released substance called substance P may push immune cells to make more allergy-causing IgE in asthma.

    NIH research Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · Torrance, United States · NIH-11424686

  • Time-limited trials to guide care for seriously ill patients in the ICU

    A real-world study tests using structured, time-limited conversations and agreed-upon treatment plans to help seriously ill patients and their families avoid non-beneficial ICU care.

    NIH research Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · Torrance, United States · NIH-11423659

  • Cellular aging and lung disease in Down syndrome babies and adults

    A study will explore how aging cells may drive lung problems in people with Down syndrome from birth through adulthood.

    NIH research Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · Torrance, United States · NIH-11411345

  • New CPET approach to tell apart heart problems from muscle weakness

    A doctor-guided study tests a modified cardiopulmonary exercise test that adds simple muscle-power measurements to better tell whether shortness of breath comes from heart disease or from weak, fatigued muscles.

    NIH research Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center · Torrance, United States · NIH-11411311

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.