Developing advanced cell models for Polycystic Kidney Disease
Cell Culture and Engineering Core (CCEC)
['FUNDING_OTHER'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-10886673
This study is working on creating special lab models of kidneys to help researchers better understand and find new treatments for Autosomal Dominant Polycystic Kidney Disease (ADPKD), making it easier for them to study the condition and test new therapies.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MARYLAND BALTIMORE (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10886673 on ClinicalTrials.gov |
What this research studies
This research focuses on creating reliable in vitro cell models for Autosomal Dominant Polycystic Kidney Disease (ADPKD) to enhance understanding and treatment options. The Cell Culture and Engineering Core (CCEC) at the University of Maryland Baltimore is developing innovative three-dimensional organoid models and murine cell lines that mimic human kidney conditions. These models will be used for mechanistic studies, therapeutic screening, and validation of human PKD cells, providing essential resources for researchers in the field. The CCEC aims to support the PKD research community by offering consultation services and high-throughput assays.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are individuals diagnosed with Autosomal Dominant Polycystic Kidney Disease.
Not a fit: Patients with other forms of kidney disease or those without a diagnosis of Polycystic Kidney Disease may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and management strategies for patients with Polycystic Kidney Disease.
How similar studies have performed: Previous research has shown success in developing in vitro models for other diseases, suggesting potential for similar advancements in PKD.
Where this research is happening
BALTIMORE, UNITED STATES
- UNIVERSITY OF MARYLAND BALTIMORE — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WOODWARD, OWEN M — UNIVERSITY OF MARYLAND BALTIMORE
- Study coordinator: WOODWARD, OWEN M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult Polycystic Kidney Disease, Autosomal Dominant Polycystic Kidney Disease