NIH-funded research R01 grant

Developing advanced brain imaging technology for Alzheimer's and dementia

Official title: Advanced thin-slab TOF-PET detector module for next generation of brain PET

Funded at Cornell University · NIH-10894248 · Data updated 2026-11-12

This study is working on making brain scans clearer and more detailed to help doctors better understand and diagnose Alzheimer's and dementia, so that patients can receive improved care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCornell University
NIH-funded
Lab location1 site (Ithaca, United States)
Project startAugust 1, 2023
Project endJuly 31, 2026
Funding year2024
Award (this year)$617,343
NIH project number5R01EB034742-02
Project IDNIH-10894248 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals experiencing symptoms of Alzheimer's disease or other dementias, as well as those at risk due to family history or genetic factors.

Less likely to help

Patients with brain disorders unrelated to Alzheimer's or dementia may not receive direct benefits from this research.

What this research studies

This research focuses on enhancing brain imaging techniques using advanced thin-slab time-of-flight Positron Emission Tomography (TOF-PET) detectors. By improving the sensitivity and spatial resolution of brain PET scans, the project aims to provide clearer and more accurate images of brain diseases, particularly Alzheimer's and dementia. The researchers will develop new detector modules and algorithms to create a dedicated whole-brain PET camera, which will significantly improve the ability to study and diagnose these conditions. This innovative approach could lead to better understanding and management of brain disorders.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and improved treatment options for patients with Alzheimer's and other forms of dementia.

How similar studies have gone: Previous research has shown promising results with advanced imaging technologies in improving the diagnosis and understanding of brain diseases, indicating a strong potential for success in this novel approach.

Where this research is happening

  • Cornell University
    Ithaca, United States
    Active

Researchers

  • Principal investigator: Thompson, Michael O — Cornell University
  • Study coordinator: Thompson, Michael O

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.