Developing a woman-controlled contraceptive using antibodies

Project 1: Industrialization of ZB-06

NIH-funded research Boston University Medical Campus · NIH-10923981

This study is exploring a new type of birth control that women can use themselves, which not only helps prevent pregnancy but also protects against sexually transmitted infections, and right now, they're testing a new film that targets sperm to keep it from fertilizing an egg.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBoston University Medical Campus NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10923981 on NIH RePORTER

What this research studies

This research focuses on creating an innovative contraceptive method that women can control, utilizing monoclonal antibodies. The project aims to develop a product that not only prevents pregnancy but also offers protection against sexually transmitted diseases. Through previous trials, researchers have tested intravaginal films containing antibodies that neutralize HIV and HSV, showing promising safety and efficacy. The current phase involves testing a new film, ZB-06, which targets sperm to prevent fertilization effectively.

Who could benefit from this research

Good fit: Ideal candidates for this research are women seeking effective contraceptive methods and those interested in protecting themselves from sexually transmitted diseases.

Not a fit: Patients who are not seeking contraception or who have contraindications to using intravaginal products may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide women with a safe and effective contraceptive option that also protects against certain sexually transmitted infections.

How similar studies have performed: Previous research has shown success with similar antibody-based approaches in contraceptive development, indicating a promising avenue for this novel method.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.