Developing a wearable ultrasound device to treat peripheral arterial disease
Official title: Acoustic-anatomic modeling and development of a patient-specific wearable therapeutic ultrasound device for peripheral arterial disease
Funded at Vibrato Medical, INC. · NIH-10603253 · Data updated 2026-11-12
This study is testing a special wearable ultrasound device that helps improve blood flow for people with peripheral arterial disease (PAD), making it easier and more convenient for patients to get treatment and potentially avoid serious complications.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vibrato Medical, INC. NIH-funded |
| Lab location | 1 site (Newport Coast, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $300,000 |
| NIH project number | 1R43HL167492-01 |
| Project ID | NIH-10603253 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with peripheral arterial disease, particularly those experiencing symptoms like claudication or advanced stages leading to skin ulcers.
✕Less likely to help
Patients with non-vascular related conditions or those who do not have peripheral arterial disease may not benefit from this research.
What this research studies
This research focuses on creating a patient-specific wearable therapeutic ultrasound device aimed at treating peripheral arterial disease (PAD). The device is designed to promote the growth of collateral blood vessels and improve blood flow in patients suffering from PAD, which can lead to severe complications like skin ulcers and amputations. By using non-invasive ultrasound technology, the treatment can be administered in an outpatient setting, making it accessible and convenient for patients. The research involves testing the device's effectiveness in improving lower extremity perfusion and overall patient outcomes.
Why it matters
Potential benefit: If successful, this research could significantly reduce the need for invasive procedures and lower amputation rates in patients with peripheral arterial disease.
How similar studies have gone: Previous research has shown promising results with therapeutic ultrasound in improving blood flow in similar conditions, indicating a potential for success with this novel approach.
Where this research is happening
-
Vibrato Medical, INC.
Newport Coast, United States Active
Researchers
- Principal investigator: Elstad, Juliana — Vibrato Medical, INC.
- Study coordinator: Elstad, Juliana
Related research
Other NIH-funded projects on the same topics.
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Contrast-free ultrasound to measure tiny blood flow in legs to help PAD
A noninvasive ultrasound approach uses new metrics to quantify microvascular blood flow in the lower leg to aid in diagnosing and managing peripheral arterial disease.
-
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-
A new ultrasound technique to measure blood flow in patients with leg artery disease
This study is testing a new, safe way to use ultrasound to check blood flow in the legs of people with peripheral arterial disease (PAD), helping doctors understand how well blood is moving in smaller vessels and potentially leading to better care for patients.
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Ultrasound-guided brain circuit targets for treatment-resistant depression
This grant tests whether focused ultrasound can safely and reversibly adjust brain circuits linked to negative mood in people with treatment-resistant depression.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.