Developing a vaccine to protect against HIV

Induction of protective antibodies for HIV vaccine development

NIH-funded research Duke University · NIH-10877768

This study is working on a new HIV vaccine that aims to help your body fight the virus better by creating special antibodies, and it's designed for people everywhere who want to protect themselves from HIV.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-10877768 on NIH RePORTER

What this research studies

This research focuses on creating an effective vaccine for HIV by using advanced technologies and immunologic tools. The project aims to induce protective antibodies that can neutralize the virus and enhance the immune response. Researchers will explore two main strategies: one to generate broadly neutralizing antibodies and another to produce protective non-neutralizing antibodies. The ultimate goal is to develop a vaccine that can be used globally to combat HIV.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at high risk for HIV infection or those interested in participating in vaccine trials.

Not a fit: Patients who are already HIV-positive or those with severe immune system deficiencies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a safe and effective vaccine that protects individuals from HIV infection.

How similar studies have performed: Previous research in HIV vaccine development has shown promise, but this approach aims to build on those findings with innovative strategies.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.