Developing a vaccine to prevent gonorrhea infections
Proteomics-Driven Reverse Vaccinology for Gonorrhea
['FUNDING_R01'] · OREGON STATE UNIVERSITY · NIH-11044128
This study is working on a new vaccine to help protect people from gonorrhea, a common sexually transmitted infection, by using special proteins from the bacteria that cause it to boost the immune system.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON STATE UNIVERSITY (nih funded) |
| Locations | 1 site (CORVALLIS, UNITED STATES) |
| Trial ID | NIH-11044128 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a vaccine for gonorrhea, a sexually transmitted infection caused by the bacterium Neisseria gonorrhoeae. The approach involves using a Virus-like-Particle (VLP) platform to deliver specific proteins from the bacteria that can stimulate a strong immune response. By selecting highly conserved proteins from various strains of the bacteria, the researchers aim to develop a safe and effective vaccine that can protect against this antibiotic-resistant infection. The study will involve designing and testing different vaccine formulations to identify the most effective combinations.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at high risk for gonorrhea, including sexually active adults and adolescents, especially those from marginalized communities.
Not a fit: Patients who are not sexually active or those who have already been vaccinated against gonorrhea may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a vaccine that significantly reduces the incidence of gonorrhea infections, particularly in vulnerable populations.
How similar studies have performed: While there have been various vaccine development efforts for other sexually transmitted infections, this specific approach using VLP technology for gonorrhea is relatively novel and untested.
Where this research is happening
CORVALLIS, UNITED STATES
- OREGON STATE UNIVERSITY — CORVALLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SIKORA, ALEKSANDRA ELZBIETA — OREGON STATE UNIVERSITY
- Study coordinator: SIKORA, ALEKSANDRA ELZBIETA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.