Developing a vaccine to prevent Entamoeba histolytica infections
Advanced Development and Clinical Evaluation of an Entamoeba Histolytica Vaccine
['FUNDING_OTHER'] · ACCESS TO ADVANCED HEALTH INSTITUTE · NIH-11060583
This study is working on a new vaccine to help protect people from a parasite that can cause serious stomach problems, and if it works well, it could be especially helpful for those living in places where these infections are more common.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ACCESS TO ADVANCED HEALTH INSTITUTE (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-11060583 on ClinicalTrials.gov |
What this research studies
This research focuses on creating and testing a vaccine against Entamoeba histolytica, a parasite that can cause severe gastrointestinal illness. The project involves formulating the vaccine components, conducting stability tests, and evaluating the vaccine's effectiveness and safety in animal models before moving to human trials. Patients may benefit from this vaccine if it proves effective in preventing infections caused by this parasite, especially in areas where such infections are common.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals living in areas with high rates of Entamoeba histolytica infections or those at increased risk due to travel or exposure.
Not a fit: Patients who are not at risk for Entamoeba histolytica infections or those with existing infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a vaccine that significantly reduces the incidence of Entamoeba histolytica infections in at-risk populations.
How similar studies have performed: While vaccines for other infectious diseases have shown success, this specific approach for Entamoeba histolytica is relatively novel and has not been extensively tested.
Where this research is happening
SEATTLE, UNITED STATES
- ACCESS TO ADVANCED HEALTH INSTITUTE — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FOX, CHRISTOPHER — ACCESS TO ADVANCED HEALTH INSTITUTE
- Study coordinator: FOX, CHRISTOPHER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.