Developing a vaccine to help treat opioid addiction
Phase 1a/1b Clinical Trials of Multivalent Opioid Vaccine Components
This study is testing a new vaccine that could help people recovering from opioid addiction by making it harder for opioids like oxycodone and heroin to affect them, and it's designed for anyone looking for new ways to stay on track in their recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10782616 on NIH RePORTER |
What this research studies
This research investigates a new approach to treating opioid use disorder (OUD) by developing vaccines that target specific opioids, such as oxycodone and heroin. The study will first evaluate the safety and immune response of the oxycodone vaccine (OXY-KLH) before moving on to a similar vaccine for heroin (M-KLH). If successful, these vaccines could help reduce the risk of relapse in individuals recovering from opioid addiction. The research aims to provide critical data on the effectiveness of these vaccines in preventing opioid misuse.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorder who are seeking treatment options.
Not a fit: Patients who are not struggling with opioid addiction or those who have not been diagnosed with opioid use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new preventive treatment option for individuals struggling with opioid addiction.
How similar studies have performed: While the concept of using vaccines for addiction treatment is novel, similar approaches have shown promise in preliminary studies, indicating potential for success.
Where this research is happening
New York, United States
- New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC — New York, United States (Active)
Researchers
- Principal investigator: Comer, Sandra D — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
- Study coordinator: Comer, Sandra D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.