Developing a vaccine for Clostridioides difficile infections
Official title: Administrative Core
Funded at Vanderbilt University Medical Center · NIH-11044214 · Data updated 2026-11-12
This study is working on creating vaccines to help protect people from Clostridioides difficile infections, which can cause serious gut problems, and it brings together a team of researchers to make sure they’re all working well together to make progress.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | March 3, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $64,721 |
| NIH project number | 5U19AI174999-03 |
| Project ID | NIH-11044214 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk of Clostridioides difficile infections, particularly those with a history of antibiotic use or underlying health conditions.
✕Less likely to help
Patients who are not at risk for Clostridioides difficile infections or those who have already been vaccinated may not benefit from this research.
What this research studies
This research focuses on the development of vaccines targeting Clostridioides difficile, a bacterium that causes severe intestinal infections. The project involves coordinating various activities among researchers to enhance collaboration and ensure effective progress towards vaccine development. Regular meetings and feedback sessions will be held to monitor advancements and address challenges. The Administrative Core will also manage compliance with NIH reporting requirements to maintain transparency and accountability.
Why it matters
Potential benefit: If successful, this research could lead to an effective vaccine that significantly reduces the incidence of Clostridioides difficile infections.
How similar studies have gone: Previous research has shown promise in developing vaccines for Clostridioides difficile, indicating that this approach has potential for success.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Lacy, Dana Borden — Vanderbilt University Medical Center
- Study coordinator: Lacy, Dana Borden
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.