Developing a vaccine for Babesia parasites that cause human illness
Antigen Discovery and Vaccine Development for Human Babesia Parasites
This study is looking into how to better understand and fight human babesiosis, a tick-borne illness, by exploring the parasites that cause it, with the goal of finding new ways to diagnose and treat the disease, and hopefully develop a vaccine to help prevent it in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10818371 on NIH RePORTER |
What this research studies
This research focuses on understanding and combating human babesiosis, a tick-borne illness caused by Babesia parasites. The team is investigating the biology and genetics of these parasites to identify potential vaccine targets and improve diagnostic methods. By analyzing the immune response and developing combination therapies, they aim to create effective treatments and ultimately a vaccine to prevent this disease. Patients may benefit from advancements in diagnosis and treatment options as the research progresses.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals who have been diagnosed with babesiosis or are at high risk of infection due to tick exposure.
Not a fit: Patients who are not at risk for babesiosis or those who have other unrelated health conditions may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of a vaccine and more effective treatments for babesiosis, significantly reducing morbidity and mortality associated with the disease.
How similar studies have performed: Other research has shown promise in developing vaccines and therapies for similar tick-borne diseases, indicating potential for success in this area as well.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Ben Mamoun, Choukri — Yale University
- Study coordinator: Ben Mamoun, Choukri
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.