Developing a vaccine and immunotherapy for Coccidioidomycosis
Project #3:Active Vaccination and Immunotherapy Against Coccidioidomycosis
This study is working on a new vaccine and treatment for Coccidioidomycosis, a fungal infection that affects many people in the U.S., to help boost your immune system and keep you healthy.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas San Antonio NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-11004672 on NIH RePORTER |
What this research studies
This research focuses on creating a vaccine and immunotherapy for Coccidioidomycosis, a fungal infection affecting around 350,000 people in the U.S. each year. The team has developed a recombinant chimeric polypeptide antigen that is designed to stimulate a strong immune response. They will explore two delivery methods, mRNA and vector-based systems, to enhance the immune system's ability to fight the infection. The goal is to produce a safe and effective vaccine that can be tested in humans.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk of Coccidioidomycosis, particularly those living in endemic areas or with compromised immune systems.
Not a fit: Patients who are not at risk for Coccidioidomycosis or those with existing severe allergic reactions to vaccine components may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a new vaccine that significantly reduces the incidence and severity of Coccidioidomycosis.
How similar studies have performed: Previous research has shown promise in developing vaccines for fungal infections, but this specific approach using rCpa1 is novel.
Where this research is happening
San Antonio, United States
- University of Texas San Antonio — San Antonio, United States (Active)
Researchers
- Principal investigator: Hung, Chiung-Yu — University of Texas San Antonio
- Study coordinator: Hung, Chiung-Yu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.