Developing a universal test for Crimean-Congo Hemorrhagic Fever virus.
Official title: PANDAA for universal, pan-lineage molecular detection of Crimean-Congo Hemorrhagic Fever virus.
Funded at Aldatu Biosciences, INC. · NIH-11013681 · Data updated 2026-11-12
This study is working on a new test called PANDAA that helps quickly and accurately find the Crimean-Congo hemorrhagic fever virus, even in its early stages, making it easier for doctors to diagnose patients in areas where this illness is common.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Aldatu Biosciences, INC. NIH-funded |
| Lab location | 1 site (Watertown, UNITED STATES) |
| Project start | March 24, 2021 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $986,903 |
| NIH project number | 2R44AI157650-03 |
| Project ID | NIH-11013681 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals in regions where Crimean-Congo hemorrhagic fever is endemic or those who have been exposed to ticks in these areas.
✕Less likely to help
Patients who do not reside in or have not traveled to areas where Crimean-Congo hemorrhagic fever is present may not benefit from this research.
What this research studies
This research focuses on creating a diagnostic tool called PANDAA that can detect the Crimean-Congo hemorrhagic fever virus (CCHFV) across various strains. The approach utilizes advanced probe-based qPCR technology to identify the virus even in its early stages, which can be challenging due to non-specific symptoms. By adapting to the genetic variations of the virus, this test aims to provide rapid and accurate results, improving diagnosis in resource-limited settings where CCHF is prevalent.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnosis of Crimean-Congo hemorrhagic fever, potentially saving lives.
How similar studies have gone: Other research has shown promise in developing rapid diagnostic tests for viral infections, suggesting that this approach could be effective.
Where this research is happening
-
Aldatu Biosciences, INC.
Watertown, United States Active
Researchers
- Principal investigator: Macleod, Iain James — Aldatu Biosciences, INC.
- Study coordinator: Macleod, Iain James
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.