Developing a universal test for Crimean-Congo Hemorrhagic Fever virus.
PANDAA for universal, pan-lineage molecular detection of Crimean-Congo Hemorrhagic Fever virus.
['FUNDING_SBIR_2'] · ALDATU BIOSCIENCES, INC. · NIH-11013681
This study is working on a new test called PANDAA that helps quickly and accurately find the Crimean-Congo hemorrhagic fever virus, even in its early stages, making it easier for doctors to diagnose patients in areas where this illness is common.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALDATU BIOSCIENCES, INC. (nih funded) |
| Locations | 1 site (Watertown, UNITED STATES) |
| Trial ID | NIH-11013681 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a diagnostic tool called PANDAA that can detect the Crimean-Congo hemorrhagic fever virus (CCHFV) across various strains. The approach utilizes advanced probe-based qPCR technology to identify the virus even in its early stages, which can be challenging due to non-specific symptoms. By adapting to the genetic variations of the virus, this test aims to provide rapid and accurate results, improving diagnosis in resource-limited settings where CCHF is prevalent.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals in regions where Crimean-Congo hemorrhagic fever is endemic or those who have been exposed to ticks in these areas.
Not a fit: Patients who do not reside in or have not traveled to areas where Crimean-Congo hemorrhagic fever is present may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnosis of Crimean-Congo hemorrhagic fever, potentially saving lives.
How similar studies have performed: Other research has shown promise in developing rapid diagnostic tests for viral infections, suggesting that this approach could be effective.
Where this research is happening
Watertown, UNITED STATES
- ALDATU BIOSCIENCES, INC. — Watertown, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MACLEOD, IAIN JAMES — ALDATU BIOSCIENCES, INC.
- Study coordinator: MACLEOD, IAIN JAMES
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.