NIH-funded research Sbir 2 grant

Developing a universal test for Crimean-Congo Hemorrhagic Fever virus.

Official title: PANDAA for universal, pan-lineage molecular detection of Crimean-Congo Hemorrhagic Fever virus.

Funded at Aldatu Biosciences, INC. · NIH-11013681 · Data updated 2026-11-12

This study is working on a new test called PANDAA that helps quickly and accurately find the Crimean-Congo hemorrhagic fever virus, even in its early stages, making it easier for doctors to diagnose patients in areas where this illness is common.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionAldatu Biosciences, INC.
NIH-funded
Lab location1 site (Watertown, UNITED STATES)
Project startMarch 24, 2021
Project endJuly 31, 2027
Funding year2024
Award (this year)$986,903
NIH project number2R44AI157650-03
Project IDNIH-11013681 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals in regions where Crimean-Congo hemorrhagic fever is endemic or those who have been exposed to ticks in these areas.

Less likely to help

Patients who do not reside in or have not traveled to areas where Crimean-Congo hemorrhagic fever is present may not benefit from this research.

What this research studies

This research focuses on creating a diagnostic tool called PANDAA that can detect the Crimean-Congo hemorrhagic fever virus (CCHFV) across various strains. The approach utilizes advanced probe-based qPCR technology to identify the virus even in its early stages, which can be challenging due to non-specific symptoms. By adapting to the genetic variations of the virus, this test aims to provide rapid and accurate results, improving diagnosis in resource-limited settings where CCHF is prevalent.

Why it matters

Potential benefit: If successful, this research could lead to faster and more accurate diagnosis of Crimean-Congo hemorrhagic fever, potentially saving lives.

How similar studies have gone: Other research has shown promise in developing rapid diagnostic tests for viral infections, suggesting that this approach could be effective.

Where this research is happening

  • Aldatu Biosciences, INC.
    Watertown, United States
    Active

Researchers

  • Principal investigator: Macleod, Iain James — Aldatu Biosciences, INC.
  • Study coordinator: Macleod, Iain James

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.