Developing a test to diagnose gut diseases in premature infants

Noninvasive biomarkers for gastrointestinal disease in preterm infants

NIH-funded research Chosen Diagnostics, INC. · NIH-10493444

This study is working on a simple and quick test to help doctors find out if preterm babies have a serious gut problem called necrotizing enterocolitis (NEC), which can be life-threatening, so that they can get the right care sooner and improve their chances of a healthy future.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionChosen Diagnostics, INC. NIH-funded
Lab location1 site (New Orleans, United States)
Project IDNIH-10493444 on NIH RePORTER

What this research studies

This research aims to create a noninvasive test that can quickly and accurately diagnose gastrointestinal diseases, particularly necrotizing enterocolitis (NEC), in preterm infants. NEC is a serious condition that affects a significant percentage of low birth weight infants, leading to high mortality rates and long-term health complications. The study focuses on developing a method that is easy to use and can be integrated into existing medical practices, ensuring that it is accessible to all healthcare providers. By improving early detection, the research seeks to reduce infant deaths and long-term health issues associated with NEC.

Who could benefit from this research

Good fit: Ideal candidates for this research are preterm infants, particularly those born with very low birth weight (less than 1.5 kg).

Not a fit: Patients who are not preterm or do not have gastrointestinal diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier diagnoses of gastrointestinal diseases in preterm infants, significantly improving survival rates and reducing healthcare costs.

How similar studies have performed: Other research has shown promise in developing noninvasive diagnostic methods for gastrointestinal diseases, but this specific approach is novel.

Where this research is happening

New Orleans, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.