Developing a technology to analyze cells in 3D cultures without damaging them
Official title: An Automated Microfluidics Technology for Minimally Disruptive Analysis of Cells and Fluids within Living 3D Cultures
Funded at New Jersey Institute of Technology · NIH-10414469 · Data updated 2026-11-12
This study is working on a new technology that lets scientists safely analyze and treat living cells in 3D cultures without harming them, which could lead to better ways to test drugs and improve tissue engineering for patients like you.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New Jersey Institute of Technology NIH-funded |
| Lab location | 1 site (Newark, United States) |
| Project start | July 1, 2022 |
| Project end | June 30, 2025 |
| Funding year | 2022 |
| Award (this year) | $416,312 |
| NIH project number | 1R15GM145610-01 |
| Project ID | NIH-10414469 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that require advanced tissue engineering or drug testing, particularly those involved in regenerative medicine.
✕Less likely to help
Patients who are not involved in tissue engineering or drug testing may not receive direct benefits from this research.
What this research studies
This research focuses on creating an automated microfluidics technology that allows for the nondestructive analysis of cells and fluids within living 3D cultures. By integrating microscopic channels and ports into these cultures, the research aims to enable continuous manipulation of fluids and cells, such as delivering nutrients or drugs, without harming the cells. This approach addresses the limitations of traditional methods that often require sacrificing samples, thus providing more reliable and continuous data. Patients may benefit from advancements in tissue engineering and drug testing that arise from this innovative technology.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments by improving how we study and test drugs on living tissues.
How similar studies have gone: While the approach of using automated microfluidics in 3D cultures is innovative, similar technologies have shown promise in other areas of biological research, indicating potential for success.
Where this research is happening
-
New Jersey Institute of Technology
Newark, United States Active
Researchers
- Principal investigator: Voronov, Roman S — New Jersey Institute of Technology
- Study coordinator: Voronov, Roman S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.