Developing a system to monitor and control anesthesia delivery using brain activity
Non-Human Primate Model for Developing Closed-Loop Anesthesia Delivery Systems
This study is testing a new system that automatically adjusts anesthesia based on brain activity, making it safer for patients, especially older adults or those who are very ill, by helping to prevent brain problems after surgery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Institute of Technology NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11140325 on NIH RePORTER |
What this research studies
This research focuses on creating a closed-loop anesthesia delivery system that continuously monitors brain function during anesthesia using advanced technology. By analyzing real-time electroencephalogram (EEG) data, the system aims to adjust anesthetic levels automatically, ensuring patients maintain the appropriate level of unconsciousness. This approach is particularly important for vulnerable populations, such as the elderly or critically ill patients, who are at higher risk for brain dysfunction after anesthesia. The study utilizes non-human primates to test the effectiveness and safety of this innovative anesthesia management system.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include elderly patients and those requiring prolonged anesthesia, such as critically ill individuals.
Not a fit: Patients who are not undergoing anesthesia or those with conditions that preclude the use of general anesthesia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of brain dysfunction in patients undergoing anesthesia.
How similar studies have performed: Previous research has shown promise in using EEG monitoring for anesthesia management, indicating that this approach could lead to significant advancements in patient care.
Where this research is happening
Cambridge, United States
- Massachusetts Institute of Technology — Cambridge, United States (Active)
Researchers
- Principal investigator: Brown, Emery N — Massachusetts Institute of Technology
- Study coordinator: Brown, Emery N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.