Developing a sprayable solution to prevent surgical adhesions after abdominal surgery
Sprayable Polymer Blends for Prevention of Site Specific Surgical Adhesions
['FUNDING_R01'] · UNIV OF MARYLAND, COLLEGE PARK · NIH-11086633
This study is testing a new spray that could help prevent painful scar tissue from forming after abdominal surgeries, making recovery easier for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF MARYLAND, COLLEGE PARK (nih funded) |
| Locations | 1 site (COLLEGE PARK, UNITED STATES) |
| Trial ID | NIH-11086633 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a new type of sprayable polymer blend designed to prevent the formation of adhesions, which are fibrous bands that can develop after abdominal surgeries. The approach aims to improve upon existing methods that are often difficult to apply and inconsistent in effectiveness. By combining a solid barrier with targeted therapeutic agents, the research seeks to enhance the mechanical properties and applicability of adhesion prevention strategies. Patients who undergo abdominal surgery may benefit from this innovative solution, which aims to reduce complications such as chronic pain and bowel obstruction.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals scheduled for abdominal surgeries who are at risk of developing adhesions.
Not a fit: Patients who have already developed adhesions or those undergoing non-abdominal surgeries may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the occurrence of painful and costly surgical adhesions in patients after abdominal surgery.
How similar studies have performed: Previous research has shown promise in using polymer blends for adhesion prevention, but this specific approach is novel and aims to address existing limitations.
Where this research is happening
COLLEGE PARK, UNITED STATES
- UNIV OF MARYLAND, COLLEGE PARK — COLLEGE PARK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KOFINAS, PETER — UNIV OF MARYLAND, COLLEGE PARK
- Study coordinator: KOFINAS, PETER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.